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An orange peel extract in which HD is the main compound can protect rat liver from CCl4-induced injury by lowering the levels of AST and ALT, and by increasing the content of glutathione, the activities of SOD and glutathione peroxidase ( 2.5.1.2 Effects of HD on hepatic lipid metabolism HD has been reported to have a therapeutic effect on lipid disorders in the liver

Kitz J, Lefebvre C, Carlos J, Lowes LE, Allan AL

After intravenous (IV) dosing in normal subjects, the volume of distribution (Vd) was 8.8 L (113 mL/kg), and the total body clearance (CL) was 47.8 mL/min

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